| Cambridge United FC v Luton Town FC 05/02/2022 | £7.50 | |
| Gillingham FC v Cambridge United FC 08/02/2022 | £7.50 | |
| Burton Albion FC v Cambridge United FC 12/02/2022 | View match | |
| Cambridge United FC v Accrington Stanley FC 19/02/2022 | £7.50 | |
| Cambridge United FC v Plymouth Argyle FC 22/02/2022 | View match | |
| Oxford United FC v Cambridge United FC 26/02/2022 | View match | |
| Wycombe Wanderers FC v Cambridge United FC 01/03/2022 | View match | |
| Cambridge United FC v Shrewsbury Town FC 05/03/2022 | £7.50 | |
| Sheffield Wednesday FC v Cambridge United FC 12/03/2022 | View match | |
| Cambridge United FC v MK Dons (Milton Keynes Dons) 19/03/2022 | £7.50 | |
| AFC Wimbledon FC v Cambridge United FC 26/03/2022 | £7.50 | |
| Ipswich Town FC v Cambridge United FC 02/04/2022 | View match |